Last edited by Kegul
Thursday, May 14, 2020 | History

1 edition of Next-generation genome sequencing found in the catalog.

Next-generation genome sequencing

towards personalized medicine

by Michal Janitz

  • 293 Want to read
  • 23 Currently reading

Published by Wiley-VCH in Weinheim .
Written in English

    Subjects:
  • Genomics,
  • Human gene mapping,
  • Chromosome Mapping,
  • Methods,
  • Medical genetics,
  • Nucleotide sequence,
  • DNA Sequence Analysis

  • Edition Notes

    Statementedited by Michal Janitz
    ContributionsWiley online library
    Classifications
    LC ClassificationsQH445.2 .N49 2008eb
    The Physical Object
    Format[electronic resource] :
    ID Numbers
    Open LibraryOL27016685M
    ISBN 103527625135
    ISBN 109783527625130
    OCLC/WorldCa299047796

      Next generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high . In principle, the concepts behind Sanger vs. next-generation sequencing (NGS) technologies are similar. In both NGS and Sanger sequencing (also known as dideoxy or capillary electrophoresis sequencing), DNA polymerase adds fluorescent nucleotides one by one onto a growing DNA .

    In NGS, vast numbers of short reads are sequenced in a single stroke. To do this, firstly the input sample must be cleaved into short sections. The length of these sections will depend on the particular sequencing machinery used. In Illumina sequencing. Next-generation sequencing has enabled cost-effective sequencing of the coding regions of all the genes in the genome or even the whole genome. We, along with several other groups, have conducted exome sequencing .

    Whole-genome sequencing (WGS) is a comprehensive method for analyzing entire genomes. Genomic information has been instrumental in identifying inherited disorders, characterizing the mutations that drive cancer progression, and tracking disease outbreaks. Rapidly dropping sequencing .   How will whole genome sequencing transform disease detection? Whole genome sequencing provides more detailed and precise data for identifying outbreaks than the current .


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Next-generation genome sequencing by Michal Janitz Download PDF EPUB FB2

What is Next-Generation DNA Sequencing. | EMBL-EBI Train. Written by leading experts from industry and academia, this first single comprehensive resource addresses recent developments in next generation DNA sequencing technology and their impact on genome research /5(2). About this book Written by leading experts from industry and academia, this first single comprehensive resource addresses recent developments in next generation DNA sequencing technology and their impact on genome research.

The NOOK Book (eBook) of the Next-Generation Genome Sequencing: Towards Personalized Medicine by Michal Janitz at Barnes & Noble. FREE Shipping on $35 Due to COVID Pages: Next-Generation Sequencing Data Analysis shows how next-generation sequencing (NGS) technologies are applied to transform nearly all aspects of biological research.

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About this book This volume covers a wide range of various fields of research, with the common thread being Next Generation Sequencing (NGS) related methods and applications, as well as analysis.

Next Generation Sequencing and Whole Genome Selection in Aquaculture comprehensively covers the current state of research in whole genome selection and applies these discoveries to the aquaculture industry specifically.

The text begins with a thorough review of SNP and transitions into topics such as next generation sequencing. "Next-Generation DNA Sequencing Informatics (2nd edition) is a book to get you well and truly started in chapters appear to flow well internally and cover the main aspects of.

The completion of the Human Genome Project in ushered in a new era of rapid, affordable, and accurate genome analysis—called Next Generation Sequencing (NGS). NGS builds upon “first generation sequencing” technologies to yield accurate and cost-effective sequencing.

Next-generation sequencing involves three basic steps: library preparation, sequencing, and data analysis. Find resources to help you prepare for each step and see an example workflow for microbial whole-genome sequencing. Next generation sequencing (NGS), a high-throughput DNA sequencing technology, provides a major change in the medical care of patients with hereditary disorders of vision and hearing.

The aim of this. Next-generation DNA sequencing (NGS) technology has revolutionized biomedical research, making complete genome sequencing an affordable and frequently used tool for a wide variety of research /5(5).

Next Generation Sequencing Next-generation sequencing technologies are revolutionising genomics and their effects are becoming increasingly widespread.

Many tools and algorithms relevant to next-generation sequencing. High throughput DNA sequencing methodology (next generation sequencing; NGS) has rapidly evolved over the past 15 years and new methods are continually being commercialized.

As the technology Cited by: This trail-blazing book gives researchers, unparalleled access to state-of-the-art DNA sequencing technologies, new algorithmic sequence assembly techniques, and emerging methods for both resequencing and genome analysis that together form the most solid foundation possible for tackling experimental and computational challenges in the genome Format: Hardcover.

An Introduction to Next-Generation Sequencing Technology Author: Illumina Created Date: 9/22/ AM. Recently several next generation high throughput DNA sequencing techniques have arrived on the scene and are opening fascinating opportunities in the fields of biology and medicine.

This book, “DNA. Written by leading experts from industry and academia, this first single comprehensive resource addresses recent developments in next generation DNA sequencing technology and their Brand: Wiley. DNA sequencing is the process of determining the sequence of nucleotides in a section of DNA.

The first commercialised method of DNA sequencing was Sanger sequencing. Next-generation sequencing (NGS), also known as high-throughput sequencing, is the catch-all term used to describe a number of different modern sequencing. The next-generation genome sequencing platforms are principally based on the immobilization of the DNA samples onto a solid support, cyclic sequencing reactions using automated fluidics devices.

Today, Next Generation Sequencing (NGS) techniques represent the next phase in the evolution of DNA sequencing technology at dramatically reduced cost compared to traditional Sanger sequencing.

A single laboratory today can sequence the entire human genome Cited by: The ultimate objective of a genome project is the complete DNA sequence for the organism being studied, ideally integrated with the genetic and/or physical maps of the genome so that genes and other interesting features can be located within the DNA sequence.

This chapter describes the techniques and research strategies that are used during the sequencing phase of a genome .